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A slow and steady revolution is sweeping the market for erectile dysfunction drugs – Cialis. Most people may not even be aware of it. Lilly ICOS, the pharmaceutical alliance, which launched the blockbuster drug Cialis, announced that the drug has achieved 1 billion dollars in global sales since launching in Europe less than two years back. In fact Cialis has become the top Erectile Dysfunction treatment in France, since January 2005, based on the latst market data, easily overtaking Viagra, the first brand to be launched in this market. It is also doing very well in United Kingdom, Italy, Germany, United States, Canada, Australia, Mexico and Brazil. So much so that a Lilly ICOS press release contained these words from Rich Pilnik, President of Lilly's EMEA region "We are very pleased with the performance of Cialis and the steady development of the brand since its launch two years ago. Millions of men suffer from ED and the growth of the market demonstrates that patients are speaking to their healthcare providers about ED and seeking treatment options." Not only has Cialis been able to expand the market but it has also eaten heavily in the market share of Viagra from Pfizer, the first drug to be launched in this market and Levitra from Glaxo-Bayer-Schering Plough. In fact Cialis was the second PDE5 inhibitor drug to become available in Europe. It is currently promoted in approximately 100 countries including the United States, Australia, Brazil, Mexico, Canada and across Europe and Asia for Erectile Dysfunction. According to Paul Clark, Chairman and Chief Executive Officer of ICOS Corporation. "Passing the $1 billion mark is an important milestone for Lilly ICOS and a great accomplishment for the Cialis team. Since 2003, men with erectile dysfunction have had a choice of oral treatments for their condition - a condition which may impact on relationships and daily life." Beyond all the hype and the jubilation is the sheer superiority of Cialis over all the other drugs available in this indication. To understand the benefits of Cialis, we need to firstly understand this complex condition. Erectile Dysfunction or Impotence is defined as the inability to ensure and maintain an erection sufficient for sexual intercourse. ED affects an estimated 180 million men worldwide . 90 percent of ED cases are related to a physical or medical condition, such as diabetes, cardiovascular diseases, and prostate cancer treatment, while 10 percent are due to psychological causes . In many cases, however, both psychological and physical factors contribute to the condition. Where physical factor play an important role PDE-5( Phosphodiaterase) inhibitors have a significant role to play. These include drugs like Sildenafil (Viagra) and Vardenafil(Levitra). But none are as good as Tadalafil(Cialis). Why? Firstly let’s understand how PDE-5 inhibitors work. They work by inhibiting the enzyme phosphodiasterase-5 which is responsible for degrading another enzyme called cGMP(cyclic Guanosine Mono Phosphate) which through a series of reactions is responsible for the synthesis of nitric oxide. Nitric oxide is an important vasodilator responsible for dilation of the blood vessels that supply blood to the penis. Thus, there is an increase in the blood supplied to the penis and this increased blood engorges the penis and leads the formation of an erection through hydraulic pressure. All PDE-5 inhibitors work in the same way but because they are different molecules, they also have different properties. The body quickly eliminates both Sildenafil and Vardenafil. Therefore their action lasts for only 4 hours, while Tadalafil(Cialis) is absorbed and eliminated slowly therefore it remains in the body for a longer period of time. Therefore its duration of action is 9 times that of other drugs - 36 hours. This ensures that Cialis will act over a whopping 36 hours and any patient on Cialis does not need to have hurried sex , but sex at his or his partner’s leisurely pace. That is why Cialis has been nicknamed as “Le Weekend Pill” in France. It allows the man to relax with his partner and have spontaneous sex. Also other drugs like Viagra act on the enzyme PDE-6, which is found in the eyes, leading to bluish discolouration of vision, which will not occur with Cialis. Cialis can be taken with a 100% fat meal and there will be no change in it’s action. The same is not true for Sildenafil or Vardenafil, which are affected by food. All this makes Cialis currently the best drug for erectile dyfunction. What further adds to it’s appeal are programmes like “The Cialis Promise” from Lilly ICOS which guarantees free trial with a rival drug in case Cialis does not work. With this kind of confidence oozing from Lilly ICOS, there is reason to believe in the promise of Cialis. Cialis is available at any neighbour chemist on providing a doctor’s prescription or one can buy Cialis online. An online prescription is generated on filling a short form and on payment through credit card, one can be rest assured of getting Cialis discreetly. What more cheap generic Cialis is also available online. This will further reduce your medical bills. The low cost is like an icing to the Cialis cake or pudding for that matter . 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Tender-handed stroke a nettle, And it stings you for your pains; Grasp it like a man of mettle, And it soft as silk remains. The common stinging nettle has long been used as a protective herb. A vase of freshly cut nettles under a sickbed is supposed to help the patient recover from whatever is ailing him or her. Nettles sprinkled around the house will ward off evil. Nettles tossed on to a fire will avert danger and carried by hand will fend off ghosts. When carried with yarrow, nettles will bestow courage. In ancient Ireland, nettles were known as “The Devil’s Apron”. Legend maintains that Roman soldiers, who used nettles for “urtification,” brought the plant to Britain. That is, they beat themselves with the herb to encourage surface blood circulation in an effort to keep warm in the dismal, damp climate to which they had been banished. The name nettle may originate with the Anglo-Saxon word netel, which in turn is derived from noedl, meaning needle. Another possibility is simply that the herb – since the Bronze Age – has been spun into fibre to make cloth, paper and fishnet, and the name originated with this usage. The botanical name, urtica, is from the Latin, urere, meaning “to sting”. At one time, nettles were actually cultivated in northern Europe to make linen, coarse sailcloth and fishnets. To make the cloth, nettles were cut, dried and soaked in water. The fibres were then separated and spun into yarn. Eventually, flax superceded nettles. But they were still being used in Scotland in the 19th century to make a crude household cloth known as “scotchcloth”. In the Hans Christian Anderson fairy tale, The Princess and the Eleven Swans, the coats the princess made for her brothers were woven from nettles. It is to be hoped in this enlightened age that gardeners will invite this wonderful herb into their garden and not regard it as a weed. Recent tests in organic gardening have confirmed that nettles make excellent companion plants, helping to produce healthy vegetables such as broccoli and conferring keeping qualities on tomatoes by impeding the fermentation process in the plant’s juices. Nettles will increase the production of essential oil in peppermint and boost the potency of all nearby herbs. Nettles in your compost heap will not only add nutrients, but also accelerate the breakdown of matter into robust humus. Nettles are a perennial to zone 2 with a germination period of 10-14 days. They prefer full sun to partial shade and like a slightly damp soil rich in nitrogen. The herb may be propagated by seed, cuttings or root division. As a vegetable, nettles are best when they’re young and tender, but for medicinal purposes the herb should be collected when the flowers are in bloom, anytime from June to September. The aerial parts of the plant are rich in chlorophyll, indoles such as histamine and serotonin, acetylcholine, glucoquinones, minerals (iron, silica, potassium, manganese and sulfur), tannins and vitamins A and C. The herb is also a good source of protein and dietary fibre. The disagreeable sting of the nettle is caused by formic acid. The herb is astringent, diuretic, tonic and hypotensive (reduces blood pressure). Nettles strengthen and support the whole body. Throughout Europe they are used as a spring tonic and general detoxifying remedy. In some cases of rheumatism and arthritis they can be astoundingly successful. They are a specific in cases of childhood eczema and beneficial in all the varieties of this condition, especially in nervous eczema. As an astringent they may be used for nosebleeds or to relieve the symptoms wherever there is hemorrhage in the body, for example in uterine hemorrhage. Research into the therapeutic properties of nettle root in the US, Germany and Japan show promise for its use in the treatment of benign prostate hypertrophy (enlargement). According to Master Herbalist, David L. Hoffmann, B.Sc.; M.N.I.M.H., conditions that benefit from the use of nettles include: diarrhea, dysentery, hemorrhoids, hemorrhages, fevers, gravel, inflammation of the kidneys, chronic diseases of the colon, eczema and cystitis. Nettles will combine well with figwort and burdock in the treatment of eczema. As an infusion, pour a cup of boiling water over one to two teaspoonfuls of the dried herb or herbs and leave to infuse for l0-l5 minutes. This should be drunk three times a day. As a tincture, take one to four millilitres of the tincture three times a day. Nettles are also antiallergenic. The herb is effective for hay fever, asthma, and skin problems due to allergies and insect bites. Ironically, nettle juice is a very good antidote for nettle stings. Nettles make good feed for livestock. In northern Europe nettles are mowed and fed to cattle, chicken and horses. For horses the herb supplies albuminoid, an excellent conditioning protein that gives the animals a sleek coat. Also a dye plant, nettles make an attractive permanent green dye. The roots boiled with alum produce yellow, which was once used to dye yarns. Because of their infamous sting, nettles require gloved hands and a long-sleeved shirt for harvesting. When cooked or dried nettles lose their sting. Steamed, they taste very much like spinach and the convention is that it is best to pick them when young. However, we made the following Nettle and Basil Soup with mature nettle leaves and it was delicious. Nettle and Basil Soup · 2 packed cups of fresh nettle leaves · 1 onion, chopped · 1 Tbsp. of butter (or a healthy cooking oil such as coconut oil) · 1 cup of milk (or milk substitute such as nut milk) · 1/3 cup of Romano cheese, grated · 2 cups of vegetable or herb bouillon · Sea salt and freshly ground black pepper to taste · 4 small-medium potatoes, peeled and chopped · 2 Tbsp. fresh basil · Sour cream or yogurt (optional) · Chopped chives and fresh parsley for garnish Sauté the onion gently in the butter in a large saucepan until translucent. After rinsing the nettle leaves, add to the pan along with the stock and the potatoes. Cook for about 20 minutes until the potatoes are soft. Add the basil, milk and Romano cheese. Allow to cool then blend in batches. Return to the saucepan and reheat. Check for seasoning, adding the salt and fresh ground black pepper as needed. Serve hot garnished with the fresh chives and parsley. 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People suffering from Erectile Dysfunction have been very quick to embrace the Impotence drug called Viagra. Nobody can rule out the effectiveness of Viagra against Impotence but there are some cases where the drug is susceptible to some major side effects. These could be in the form a heart disease, diabetes and blindness. New studies reveal the possible impact of Viagra on the visibility of a person. According to British Journal of Ophthalmology, a person may suddenly lose his eyesight resulting in Blindness. The doctors treating the problem, have warned their patients against the new fall out of Viagra. Experts working on the subject feel that the drug could be reducing the flow of blood to the optic nerves resulting in the damage. Erectile Dysfunction drugs work on the mechanism of transferring more blood into the penis. The amount of blood being limited results in improper distribution of blood to other parts of the body. This may be one of the causes of blindness in people consuming the drug. The manufacturers though, have criticized the new study saying the study is very brief and there is no clear indication of “Viagra” being solely responsible for Blindness. Studies are still underway to find more and more cases, where people have suffered from sudden blindness after consuming Viagra. The researchers continue to encourage men to have the consultation of a physician before going any further with Viagra. FDA (Food and Drug Administration) has reported that the recent cases of blindness may have been due to diabetes and heart problems that people carried before consuming the drug. However, it has been known that the problem does affect people suffering from Erectile Dysfunction and the damage is more lethal in people consuming the blue bill. The manufacturers of Erectile Dysfunction drug have different views regarding the whole issue. They say the results could vary depending on the patient’s observational nature, his recalling capacity and the biasness of the interviewing person. truth about penile enlargement penis enlargement pills review cheap penile enlargement pills penis girth enlargement home penis enlargment herbal natural penis elargement male penis enhancement top penis elargement pills penis enlagement surgery cost

Genital Warts symptoms are quite easy to identify, but many people ignore the symptoms of genital warts and do nothing about them. All warts are caused by the Human Papilloma Virus. HPV is the most rapidly spreading STD in America and affects more people than HIV-aids. There are about 5 million new cases reported each year, and this number is growing all the time. It is important to be able to identify genital warts symptoms, so you may treat them immediately. There are many carriers of the Human Papilloma virus who do not even have any Genital Warts symptoms. In fact, most carriers of the virus, don't even have any warts! The virus is able to lay dormant in the body for months or even years, and can be passed from one person to another through sexual intercourse. So it is possible to pass the virus on, without having any genital wart symptoms at all. Genital wart symptoms are normally quite obvious. Small bumps or growths appear in the genital region, including in and around the anus, vagina and penis. They can appear as individual growths or they can group together in clusters. Some of these clusters may have a cauliflower-like appearance. They range in color from whitish or grey looking to red, pink or skin color. Unless they become lacerated and bleed, genital warts are usually not painful but may be itchy and irritating. It is best to stick to natural methods for successful treatment. vimax penis enlargement picture vigrx results penis enlargment picture home penis enlargment penis enlargement surgery photo manual penile enlargment exercise penis enargement fact pnis enlargement before and after penis enlagement surgery cost

What could possibly be worse than struggling with a painful condition and feeling ashamed to discuss the problem because of its intimate nature? Such is the case for many suffering with pudendal neuralgia, a little known disease that affects one of the most sensitive areas of the body. This area is innervated by the pudendal nerve, named after the Latin word for shame. Due to the location of the discomfort combined with inadequate knowledge, some physicians make reference to the pain as psychological. But nothing could be further from the truth. Unfortunately, discussing the condition with gynecologists, urologists and neurologists often proves fruitless since most know nothing about the condition and therefore cannot diagnose it. Pudendal neuralgia is a chronic and painful condition that occurs in both men and women, although studies reveal that about two-thirds of those with the disease are women. The primary symptom is pain in the genitals or the anal-rectal area and the immense discomfort is usually worse when sitting. The pain tends to move around in the pelvic area and can occur on one or both sides of the body. Sufferers describe the pain as burning, knife-like or aching, stabbing, pinching, twisting and even numbness. These symptoms are usually accompanied by urinary problems, bowel problems and sexual dysfunction. Because the pudendal nerve is responsible for sexual pleasure and is one of the primary nerves related to orgasm, sexual activity is extremely painful, if not impossible for many pudendalites. When this nerve becomes damaged, irritated, or entrapped, and pudendal neuralgia sets in, life loses most of its pleasure. So, where exactly is the pudendal nerve? It lies deep in the pelvis and follows a path that comes from the sacral area and later separates into three branches, one going to the anal-rectal area, one to the perineum, and one to the penis or clitoris. Since there are slight anatomic variations with each person, a patient’s symptoms can depend on which of the branches are affected, although often all three branches are involved. The fact that the pudendal nerve carries sensory, motor, and autonomic signals adds to the variety of symptoms that can be exhibited. Because pudendal neuralgia is uncommon and can be similar to other diseases, it is often misdiagnosed, leading some to have inappropriate and unnecessary surgery. Early in the diagnosis process, it is crucially important to undergo an MRI of the lumbar-sacral and pelvic regions to determine that no tumors or cysts are pressing on the nerve. In addition, the patient should be screened for possible infections or immune diseases, as well as having an evaluation by a pelvic floor physical therapist to determine the health of the pelvic floor muscles and to uncover whether skeletal alignment abnormalities exist. An accurate patient history is needed to assess whether there has been a trauma or an injury to the nerve from surgery, childbirth, or exercise. Tests that offer additional diagnostic clues include sensory testing, the pudendal nerve motor latency test, and electromyography. A nerve block that provides several hours of relief is another tool that helps to determine if the pudendal nerve is the source of pain. One of the most common symptoms that accompanies pudendal neuralgia is severe depression. Some people with the disease have committed suicide due to the intractable pain. For that reason, it is important to consider antidepressants, as they can help lessen the hypersensitivity of the genital area in addition to relieving bladder problems. Certain anti-seizure drugs reportedly help to alleviate neuropathic pain while anti-anxiety drugs provide substantial relief of muscle spasms and assist with sleeping. Uninformed physicians are reluctant to prescribe opiates for an illness that shows no visible abnormality, yet the desperate nature of genital nerve pain requires that opiates be prescribed for these patients. While medications are not always satisfactory, they do help take the edge off of the pain for many people. Until the correct treatment is determined, it is imperative that patients with pudendal neuralgia receive adequate pain management since the pain associated with this illness can be intense. Treatment depends on the cause of distress to the nerve. When the cause is not obvious patients are advised to try the least invasive and least risky therapies initially. Physical therapy that includes myofascial release and trigger point therapy internally through the vagina or rectum assists with relaxing of the pelvic floor, especially if pelvic floor dysfunction is the cause of nerve irritation. If no improvement is found after six to twelve sessions, nerve damage or nerve entrapment might be considered.Botox is now used in medical settings to relax muscles and shows promise when injected into pelvic floor muscles; though finding a physician adept at this treatment is difficult.Pudendal nerve blocks using a long-acting analgesic and a steroid can reduce the nerve inflammation and are usually given in a series of three injections four to six weeks apart. If physical therapy, Botox, and nerve injections fail to provide adequate relief, some patients opt for pudendal nerve decompression surgery. There are three published approaches to pudendal nerve decompression surgery but there is debate among members of the pudendal nerve entrapment community as to which approach is the best. Since there are advantages and disadvantages to each approach, patients face considerable confusion when deciding which type of surgery to choose. Because there are only a handful of surgeons in the world who perform these surgeries, most patients have to travel long distances for help. Moreover, the recovery period is often painful and takes anywhere from six months to several years since nerves heal very slowly. Unfortunately, early statistics indicate that only 60 to 80 percent of surgeries are successful in offering at least a 50 percent improvement. Patients whose surgeries are not successful or who do not wish to pursue surgery have the option of trying an intrathecal pain pump which delivers pain medication locally and helps to avoid some of the side effects of oral medications. Others pursue the option of a neurostimulator either to the sacral area or directly to the pudendal nerves. These are relatively new therapies for pudendal neuralgia so it is difficult to predict success rates. Some pudendalites have devised ingenious contraptions for pain relief ranging from u-shaped cushions cut from garden pads all the way to balloons filled with water, frozen, and inserted into the vagina. Most have a favorite cushion for sitting and many have special computer set-ups for home and office use in order to avoid sitting. Generally speaking, jeans are a no-no, so patients revise their wardrobes to include baggy pants and baggy underwear – if they are able to tolerate wearing underwear. Clearly more research is required to find effective methods to better manage the pain and debilitation of pudendal neuralgia. But in the meantime, friends and family close to those who have this devastating illness play a huge role in helping patients cope, thereby maintaining the best quality of life possible. Support, love and understanding are of primary importance for those suffering with this affliction.