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The Prostate: Part I – BNP What is situated below a body of water, has four zones and is commonly associated with venial pleasures. No it is not some romantic European city, but rather a walnut sized male organ that serves important procreative functions. It also happens to be an organ that plagues men as we age. This organ or gland is the prostate. This is the first of two articles on the male prostate. This article will focus on a disease process that affects older men, something we refer to as benign prostatic hyperplasia (BPH). BPH is a non-cancerous growth in the size of the prostate gland that impairs the flow of urine out of the bladder. The second article will focus of prostate cancer. But first a little about the small yet important male organ. The gland is located just below the bladder. It usually measures one inch by one-and-a-half inches (approximately the size of a walnut). It surrounds the urethra (the tube that takes urine out of the bladder). It is responsible for producing a fluid important in male sexual function. In the past the prostate was described as having “lobes”, but today we refer to it as having concentric zones. These zones are important both on an anatomical as well as histological level. We can separate pathology along these zones as well. For instance most all cancers occur in the peripheral zone while the benign process of enlargement occurs almost exclusively in the transitional zone (which only occupies about 5% of the total prostate volume). The prostate gland is also made up of different cell types. Cancer cells develop from the epithelial cells, but it is the interaction with stromal cells that is important in the behavior of the cancer. BPH develops from an interaction between these cells as well, but it is complex and poorly understood. Testosterone and other hormones and their interactions with this gland are hot topics of research in understanding prostate disease. The prostate gland produces most of what is found in the male ejaculate. The average volume is about 3 mL. This is less than a teaspoon and only 1% of it is sperm. The majority of the semen volume is made of products of the seminal vesicles and the prostate. The male ejaculate is very rich in potassium, zinc, citric acid and fructose. Along with these substances it also contains prostaglandins. There are many other unusual substances found in the semen. Not all is know about their function or purpose. This important male organ is a complex mix of anatomical structures and cell types that make it possible for human reproduction. However beyond the reproductive years of men, this organ becomes one of burden rather than usefulness. We will discuss the finer points of BPH and how to best avoid it and if plagued with it, treatment options. BPH typically affects men from their fourth to fifth decade of life and beyond. Several hormones come into play that have a drastic effect on the transitional zone (the zone that is most central and surrounding the urethra). Namely a metabolite of the male androgen Testosterone called Dihydrotestosterone (DHT) plays a big part on the enlargement of cells of the prostate and the encroachment on the urethra. There are several signs and symptoms that correlate with BPH and they are: slow urinary flow, the urge to urinate all the time, nighttime urination, enlargement and distension of the bladder with continuous urine leakage (incontinence) and urinary obstruction. Autopsies suggest that more than 90% of men older than 70 years have BPH. The average age for symptomatic development is about 65 years for white Americans and about 60 years for African-American men. Ways to prevent the effects of DHT on the prostate gland and the ensuing enlargement are via medications that block the enzyme 5-alpha-reductase, which converts Testosterone to DHT. Proscar is such a drug commercially available through a pharmaceutical company. Proscar works on blocking the effects of androgens on the epithelial cells and can actually shrink the size of the prostate making some of the symptoms of BPH resolve. Alternatively two FDA approved drugs that aid in symptoms of BPH (but act differently than Proscar) are Hytrin and Cardura. Both Hytrin and Cardura are drugs in the alpha1-blocker class. Originally researched as a centrally acting blood pressure reducer for patient with hypertension, it was discovered that this drug would actually relax the prostate tissue surrounding the urethra making symptoms of BPH resolve. Side effects generally include low blood pressure, dizziness, and nasal stuffiness. While neither of these two drugs will “cure” or reverse the process, they certainly do provide symptom relief for the patient plagued with BPH. Another way to treat this disease and a more natural approach is the use of herbs know for their anti-androgenic effects on the prostate. These include the well-studied Saw Palmetto herbal extract that blocks 5-alpha-reductase in the same manner as the prescription drug. Saw Palmetto taken in a standardized dose of 160mg twice daily has shown increased urine flow, with minimal side effects. Saw Palmetto is an herb indigenous to the Lowcountry of Georgia and South Carolina. Pygeum Africanum is shown to do the same yet it is not as effective and there is a fair degree of stomach symptoms. Pygeum is derived from an African evergreen tree. Stinging Nettles (Radix urticae) is another herb used widely in Europe for prostate health that has been shown to lower the residual urine volume in men with enlarged prostates. These phytotherapeutics (plant derived medicines), used and described by the Egyptians as far back as the 15 Century B.C., have a common compounds called phytosterols. The most effective phytosterol is beta sito sterol for BPH. None of the medications or herbs has been shown to prevent prostate cancer. These prescription medications and herbs are for the treatment, reduction in size or prevention of the benign process of enlargement of the prostate. Prostate cancer prevention and treatment is by other means and the subject of the next article. Besides the herbal and drug therapies there are a few surgical therapies worth mentioning. These include the most common transurethral resection of the prostate or TURP. This is where under the care of an urologist the constricted urethra within the prostate gland is “reamed out” thus mechanically or surgically widened the opening. A variant of this is the transurethral incision of the prostate (TUIP) where an incision rather than resection of the tissue is performed. A suitable procedure for patients with prostates 100 mL in volume. This involves an abdominal operation and removal of the whole prostate. Of course symptoms mentioned above for TURP are of greater frequency with this more radical procedure. There is also thermotherapy (a type of microwave treatment) that alleviates irritative symptoms, but not much is available in long-term results in the medical literature. And finally stent placement is an option. This can be used in selected cases of patients with a poor general condition and in the non-operative candidate. Symptoms of BPH include: Obstructive symptoms: Hesitancy in initiating voiding (trouble getting started) Weak urinary stream, prolonged voiding Post-voiding dribbling (mild incontinence) Sensation of incomplete emptying Nocturia (night time urination) Overflow incontinence Acute urinary retention (very painful condition) Irritative symptoms: Dysuria (discomfort in urination) Frequency Urgency Scoring BPH: The American Urological Association Symptom Index (AUASI) and International Prostate Symptom Score (IPSS) are now considered the gold standard measurement tools for the assessment of BPH symptoms and response to treatment. Both questionnaires can be used by a physician in a clinical practice to quantify the subjective symptoms of BPH and monitor therapies. Part II in this series will cover annual examination of the prostate, blood testing, prostate cancer. It will also cover prevention and treatment of prostate cancer. Reference: http://www.prostatehealth.com Lowe, FC. Et al, Phytotherapy in treatment of benign prostatic hyperplasia: a critical review. Urology 48:12-19, 1996 Dreikorn, K. et al, Stellenwert von Phytotherapeutica dei der Behandulng der benighnen Prostatahyperplasia. Urologe (A)34:119-129, 1995 Fitzpatrick, J.M. et al, Phytotherapeutic Agents in Management of Symptomatic Benign Prostatic Hyperplasia. Urological Clinics of North America. 22:407-412, 1995 Wilt T, Ishani A, Mac Donald R.. Serenoa repens for benign prostatic hyperplasia. The Cochrane Database of Systematic Reviews 2002, Issue 3. Art. No.: CD001423. DOI: 10.1002/14651858.CD001423. [Research by Sagalowski and Wilson, 1998] © 2005 penis enlagement exercise penis enlagement surgery cost free penis enargement technique free exercise tip for penis enargement vimax penis enlargement patch free penis enlargment exercise penis elargement operation vimax penis enlargement

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The other day, my mother, who compulsively shops for anything you can think of, bought me a bag of sunflower seeds, as I went through a phase of eating them about a decade ago. First of all, this was a completely redundant gesture, as they were just the seeds, and everyone knows that sunflowers seeds taste of absolutely nothing at all, and the only pleasure to be derived from them is cracking the zebra-coloured shell to extract them. No good deed is without merit, however, and in eating them I did manage an idea, which, as those who know me will tell you, is a laborious and taxing process at best. According to the packaging (which, perhaps naively, I find no reason to doubt) these sunflower seeds were bought in a branch of Boots and are part of a "meal deal." Now who, exactly, aside from perhaps squirrels and other small fluffy mammals, would ever consider sunflower seeds a "meal" ? Granted, perhaps Boots receive a lot of custom from numerous pigeons and small tits, but this still doesn't explain how I ended up with them as my mother doesn't even HAVE small tits. Sorry, I seem to have digressed and in doing so swerved perilously close to the territory of the "fat momma" joke, which I'll avoid. Meanwhile, back on the subject at hand, why is Boots (are Boots? is Boots? I hate shops with no apostrophes) selling food in the first place?! If a butcher had a deal on moisturiser and sun-tan lotion, I think I personally would give it a miss, but somehow a shop that's know for medicines and cosmetics has started offering meals and none of us has batted an eyelid. Food in general, now that I mention it, has been getting stranger, lately. McDonalds, in a frankly ludicrous attempt to improve it's image, has started offering salads as a direct result of Morgan Spurlock's "Super Size Me." Something about this bothers me, and I can't quite put my finger on it. Kudos to Mr. Spurlock for shaking an empire to it's core, it's impressive by any standards and far more than the more high-profile Michael Moore has managed to do. (Although one does suspect Moore eats all his meals at McDonalds and just forgot to film it...) McDonalds, though, is about grease. It's about grease, and junk, and things that will, probably, give you a McCoronary sometime before you make it back to your car A coronary which, by all accounts, you can make bigger and more life threatening for a bargain 30p. McDonalds isn't SUPPOSED to offer good food. Everyone knows that McDonalds is bland and bad for you, in the same way we know that alcohol is bad for us and we'll all regret it in the morning. Several months ago I thought I'd have a go at a McDonalds chocolate donut, and it was f*cking horrible. I remember remarking to those around me in my witty, Wilde-esque style, "This is f*cking 'orrible." Doesn't matter. I still have one whenever I go in, now, and they're still terrible. My point is this: NOBODY goes to McDonalds for a salad. In fact, I wouldn't trust anyone who did. I think I'll add that to my list of character indicators. Never listen to anyone who doesn't like "Columbo", and never trust anyone who goes to McDonalds for a salad. Salads go against the whole POINT of McDonalds, and I personally think that they should have more balls than to run for cover when their "secret" gets out. Tobacco companies have known for years that cigarettes kill you, as have the public, but they don't suddenly branch out and start a new line of Malboro Lollipops as a healthy alternative. Another thing that's worried my lately, food-wise, is the reappearance of Pepperami. For those too young to remember, or those living in another country, Pepperami is best described as a stick of peppered meat in a wrapper. I've always been bothered by them, principally because nobody has yet proved to my satisfaction that it isn't just the spiced penis of some unknown animal that the snack-hungry public has sent rocketing towards extinction, but over the years I sort of forgot about them. Now, all signs (TV adverts, posters, the Beast running loose in the streets of Bethlehem) point to it coming back. We should be on our guard. Now, some people may level the fair and accurate criticism at me that everything I write has no real structure; that I'm prone to going off on tangents and that I always end abruptly and inconclusively. This is true. To these people, however, I say that if you can find another article on the web that goes from Sunflower seeds to animal penis by way of a chocolate donut, then good luck to you! pnis enlargement technique penis enhancement result com enlargement pennis pennis pump pennis enlargement patch natural penile enlargement pills penis enlargment operation penis enargement device cheap vig rx penis enlarement excercises

I’ve yet to meet a man who thinks that his penis is big enough. Of course, I know that hypothetically such men exist. I’ve read forum postings from men who say: “Oh, I don’t need extra inches”. Still, I haven’t actually met a member of this rare breed. All the men I know want to increase their penises, even though they are unlikely to openly admit their dream or discuss the issue. Despite recent scientific advances which have made penis enlargement far easier than before, men are still reluctant to discuss penis size. Unless they can back their bragging up with a truly massive member. In that case, bragging becomes habitual and very annoying. We’re living in the age of big things. Big planes, big buildings, big trucks. Big penises. Everybody can join the trend and pick one of the many methods to enlarge his penis. This is a pretty normal thing to do for a man with a small penis. What I really don’t understand is when men sporting six or even seven-inch penises are interested in penis enlargement. Nothing and no one has the right to prevent a man from enlarging his penis, but if he’s already big enough why on earth would he want to be even bigger. In theory, the only limit on penis size is the body’s capacity to keep lengthening the tissues in question. In practice, however, men should take a minute to think that many, if not most, women cannot easily accommodate a penis longer than 8 inches. Even 8 inches is a bit big for a lot of women, but a penis this size can still be used with ease. Above 8 inches in length, the penis turns into some sort of fashion or power statement. There’s no practical use for anything above 8 inches, unless the owner chances himself upon a really tall lady who happens to have a longer than usual vagina. While the vagina can stretch to accommodate most penis sizes, an 8-inch penis can be a genuine threat to the uterus. Trust me, the repeated bashing of the cervix by the penis head is not on any woman’s “Things I’d like to experience” list. Moreover, vaginal orgasm is not achieved by deep penetration of the vagina. The most sensitive part of the vagina is a 4-inch stretch of tissue located at the vagina’s entrance. So, as you can see, it’s a good idea to know when enough is enough. Trying to go the extra mile and get that 10-inch penis is a feat of willpower, but there’s no practical purpose to it. There’s little pleasure in being hurt by the penetrating penis, so many women will refuse to have sex with a man who’s too well endowed, while others will insist on being very careful. Frankly, the last thing on my mind when I’m all undressed and ready to go is to be careful. penis girth enlargement penile enlargment patch penis enargement surgeries top penile enlargment pills natural penis enlarement technique vigrx enhancement vig rx store cheap penis elargement pills penis enlarement excercises

It has been found that almost every man over the age of 60 will develop one of the numerous conditions associated with the prostate gland. Many of these conditions tend to exhibit only mild symptoms until they are well developed. This means that if you are affected, you may not even realise that you have a problem. One of such conditions is known as Prostate hyperplasia, also known as Benign Prostate Hyperplasia (BPH). Although it is not cancerous, it can cause the same prostate symptoms as prostate cancer. Prostate hyperplasia is present in about 90% of men over the age of 80. However, unless it causes the prostate gland to become grossly enlarged the symptoms are relatively mild and attributed to the rigors of old age. The cause of prostate hyperplasia is not accurately known. Many researchers and oncologists believe that it is a hormone related condition. The male hormone testosterone is converted to a secondary hormone called dihydrotestosterone naturally in the body and when this secondary hormone binds with specific receptors in the tissues of the prostate gland, cellular growth and division becomes over-stimulated. Thus the prostate gland becomes enlarged so producing prostate hyperplasia. Certain families of drugs can be used to reduce the amount of testosterone in the body or to stop the available testosterone from binding with the receptors in the prostate gland. This acts to stop prostate hyperplasia from developing further and may even reduce the size of the prostate gland over time. Unfortunately drug therapy for prostate hyperplasia is an ongoing therapy and if diagnosed with the condition you will be required to take drugs daily for the rest of your life. Prostate hyperplasia symptoms are very similar to those of prostate cancer. Do take action if you notice the following: * Difficulty urinating * Urinary leakage * Pain when urinating * A feeling of urgency to urinate * Increased night time urination * Any other problems associated with urinating As mentioned above prostate hyperplasia is usually easily controlled and treated with simple drug regimes. But if the symptoms are due to cancer, then surgery may be required. Still you should not imagine the worst. A diagnosis of prostate hyperplasia does not necessarily mean that you are going to have prostate cancer. Admittedly some cases of prostate hyperplasia do progress and become cancerous. However, with early and continued treatment, the condition can be effectively controlled and enlargement of the prostate gland reduced. prosolution truth about penis enlagement pills vimax penis enlagement discount vig rx male penis enlagement penis enlargment supplement home penis enlargment penis enargement fact penis enlarement excercises

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